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May 24, 2022
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Scot: So will testosterone solve all my problems as a man? That's today on "Who Cares About Men's Health," providing information, inspiration, and a different interpretation about men in men's health. He brings the MD to the show. Ladies and gentlemen, Dr. Troy Madsen.
Troy: Yeah. Ready to talk about testosterone. I am curious, very curious. Where do we go with this? What do we do?
Scot: Offsetting the MD, I bring the BS. My name is Scot Singpiel. And Mitch, he's responsible for bringing the microphones. Welcome, Mitch.
Mitch: Hello. Hi.
Scot: I think Mitch needs some testosterone. You know how low key he is.
Mitch: It's low T day. I mean, based on everything I see on the internet, that's got to be what's going on.
Scot: Well, yeah. I mean, you go to the internet . . . I'm going to do my impersonation of the internet. You ready for this?
Mitch: I love it.
Scot: All right. You're, like, "You have low energy? You've got to get some T. You putting on a few pounds of fat? You've got to get some T. You having trouble sleeping? You've got to get some T." That's my impersonation of the internet. It's the answer to everything.
Troy: It is. It cures everything.
Scot: Yeah. So we're going to find out if that is actually true or not with Dr. John Smith.
So, Dr. Smith, what is the common complaint you get when somebody comes to you and they're interested in testosterone treatments? What problem are they trying to solve? What are they trying to cure? All the things I talked about? Something else?
Dr. Smith: Absolutely. I mean, I think the thing about testosterone is the symptoms are so wide-reaching -- fatigue, cognition, erectile issues. They've heard on the internet, or they've talked to a friend who's on testosterone, and they're like, "Man, it just changed my life. It fixed everything." Which in some people's cases that may be true, but for most people, it definitely can play a role in helping them out, but I don't think it's the cure-all that you're talking about, that the internet shows. It's not making Frank Thomas who he is today.
Scot: And that's dangerous, right? Because you can get testosterone without even having a face-to-face conversation with a doctor, right? You can essentially just order it online. Is that true or is that overstated?
Dr. Smith: I think some of the newer companies you've got out there that are making things available . . . hopefully you're getting at least a video conferencing going over your medical history with someone who's a medical provider, whether it be a nurse practitioner, a PA. Hopefully you're talking with a physician. If they're not doing it that way, they're doing it wrong.
But testosterone is one of those things where it can be very helpful. I have quite a few patients that are on it, and I think it is one of those things that can definitely benefit people. But the extent that it benefits them kind of varies between patients.
Scot: Testosterone, I get the impression that it's probably not a do-it-yourself sort of a thing. It's not something you want to, as a layperson, just dive into on your own. Why is that?
Dr. Smith: Well, there are certain . . . everything has a risk and a benefit, and testosterone is no different. For people who have low testosterone, replacing it can really make a difference. It can give you that increased boost of energy, help you with weight loss, help you with metabolism, help with sleep. It can help with erections. I mean, it can help with cognition in people who have low testosterone. However, it's not necessarily the thing that's going to fix all those problems.
And oftentimes I'll go through people's history and say, "Hey, man, your testosterone is normal. Adding more to the mix isn't likely to fix things. We should look at other issues." And so I think really just taking that deep dive and seeing if it's something that is right for you is important.
Troy: I guess, John, I've seen all this stuff Scot mentioned, you see all these things on the internet, you see TV ads, etc. Yeah, I think I wonder myself, "Man, is my testosterone low? Should I be worried about this?" At what point do you tell people, "You should get your testosterone level checked"?
Dr. Smith: I think if you've looked at some of the other . . . if you've talked to your primary doctor and kind of gone over things, the usual suspects of a thyroid issue or vitamin deficiencies, things like that that they check a lot, if those are all normal, I think it's completely reasonable to look at it.
Some people say, "Oh, well, my dad had low testosterone and I got it checked in my 30s." But if you look at the facts of the matter, about 40% of people over the age of 45 have a testosterone level of 300 or less. And so that's a decent amount of the population that's out there. And so I think if you have an interest in it, it's okay to ask to have it checked because it's better to know and to at least know what your options are where it may be a benefit to you.
Scot: And how do you do that, then?
Dr. Smith: So your regular doctor can check it. You can make an appointment with a men's health specialist like we have at the University of Utah. We have a men's health group with multiple different providers. We have nurse practitioners, PAs, and multiple MDs and DOs that can take care of your needs as far as checking the hormones. But that's the first thing that we do.
And hormones, ideally, should be checked before 10:30 in the morning because our bodies spike testosterone between the early hours of the morning. Usually people will say between 4:00 a.m. and 10:00 a.m. in the morning. And so we want to check it to see what your body is actually doing.
If you're low in the morning, the odds are that you're high in the afternoon are going to be really slim to zero because your body spikes it in the morning to give you that boost of the hormones that you need to get you through the day.
Scot: And when you take a look at that test, it's a range, right? So a man gets the test done and you've got some numbers and there's a range. And what does that tell you? Let's pretend I'm at the low end of the range, but I'm still considered normal. Is that somebody that you would suggest testosterone therapy for?
Dr. Smith: I think a lot of it is the discussion that you have with the patient. So the range is huge too. If you look at the range, most labs are between 300 and 1,000. Some are a little less, some are a little more, but just for intents and purposes of this discussion, about 300 to 1,000.
So let's say, Scot, you're at 350. Well, what does that mean? Insurance requirements say that we've got to get two tests that show a low value before 10:30 in the morning. So let's say we've done that. You come in, your first one was 350, your second one was 340 or 338. What do we do from there? Well, then we have a discussion.
And I think in a lot of those folks, it is reasonable to discuss therapy. People outside the normal range, it's obviously okay to discuss that as well, but people tend to feel better in a range around 400 to 700. Sometimes, some people will say 600 or higher. There's a lot of different variability out there between who you talk to about it.
But again, if you're feeling the symptoms of fatigue, decreased libido, decreased erectile quality, some of those things are really hitting you hard, and you're like, "I'd love to try testosterone to see if it would help some of those symptoms," I think it's completely reasonable to do that.
Mitch: But insurance won't cover it unless you are beneath that range?
Dr. Smith: Not necessarily. Insurance wants to see that you're in the low. Really, I think it's reasonable for anybody that's 350, 400, and below. You can talk to them about testosterone replacement therapy. And if there's benefit there, insurance usually won't balk at it. And if they do, and it is helping you, cash pay for this stuff is not obscene.
Mitch: I'll just disclose. Now, I had my testosterone levels checked after we did a previous episode, and my number is right around 400. And my primary care provider is like, "Oh, no, you don't need to. We don't need to. There's no need to talk about testosterone therapy." And so I've kind of put it in the back of my mind.
But then at the same time, you have the weird people on the internet that they say you need to be 600 or 1,000 or above to be healthy. And it's just like if I'm right there, I'm at the 400, maybe it would be helpful. What would you say to someone in my situation?
Dr. Smith: I think you've got to look at the whole picture, but I think it's definitely something that you could consider. Again, most primary care doctors don't do a lot of hormone replacement, so they're going to say, "Hey, you're well within normal range. We're not going to touch it. We're not going to do anything," because that's their comfort zone.
This is the thing that I do every single day where I get people sent from their primary care doctor to talk about this stuff. And I think it's an in-depth conversation of, "Hey, let's look at the whole picture. Is there anything else going on that's a problem, or could be seen as a problem? Do you have a thyroid issue? What is your BMI? How does your weight look? What's your exercise routine?" and things like that, because those things can be done before supplementing testosterone.
And there are some interesting numbers out there with diet and exercise. If people will lose weight of 10 pounds or so, you can increase your testosterone by 100 points by losing 25 pounds and getting diet and exercise.
But a lot of times, it's hard to get the motivation to go do diet and exercise when you're overweight and you're really lethargic. And so it's like, "Would testosterone help me get there?" and a lot of those things as well.
And so again, exercise 15 minutes a day for 6 months of moderate intensity exercise will increase your testosterone by 22 points. And then if you're exercising for 30 to 40 minutes a day, you'll increase it by 50 to 60 points. And so again, there are things you can do other than testosterone if you're kind of in that range, and any of those things fit.
Now, Mitch, I know you're super fit, so that doesn't really . . .
Mitch: Yeah, I'm the fittest guy.
Dr. Smith: . . . matter for you. But if those are things that you can do, those are modifiable things you can do in your life to increase your testosterone naturally.
Mitch: Got you.
Troy: You mentioned diet also, John. I mean, it sounded like we're talking more about weight loss here, but are there any kind of dietary changes in terms of foods you're eating or foods you can eat or even supplements that would increase your testosterone levels without actually having to go for any sort of hormone replacement therapy?
Scot: Raw eggs and meat, right?
Dr. Smith: Right. Exactly.
Troy: Well, sure. Yeah.
Dr. Smith: You've seen Gascon in "Beauty and the Beast." That's how he got so huge.
Troy: Exactly.
Dr. Smith: There are no real big things that are out there that are known to necessarily just be super beneficial, other than eating as clean as you can.
Testosterone is a hormone and hormones are built on a backbone of cholesterol, so they're kind of fat. They're built on fat. And so when you have excess fat tissue, sometimes the hormones like to hang out there because they don't love water. And so you'll find that people may have a higher testosterone level when they lose that body weight, because now they don't have as much body fat and that testosterone is able to kind of circulate. Plus, you're in better health and your body is able to just do what it does better.
Troy: Speaking of our concerns . . . obviously, Mitch has thought about it. I've thought about it. I know, Scot, you've told us before you've had your testosterone level checked. I think a lot of men wonder about this, and I think we get concerned and we say, "Hey, maybe I don't have a lot of energy," whatever it might be. Of those who come in to get tested, what percent really have low testosterone?
Dr. Smith: I mean, my practice is kind of skewed, because by the time a lot of these guys get to me, they've already had it checked with their primary doctor who's not going to treat them unless they're outside of the normal range. And then when they are, they get referred to our office. A lot of primary care doctors don't love treating testosterone patients and they know that that's kind of what we do.
And so I get a skewed percentage. Most of the people who come in and are looking for testosterone have already kind of been pre-screened, so they are low. I would say a vast majority, at least three-quarters of the people that I see, already have testosterone levels that come back and are low and they're there to talk about therapy as a referral from their primary doctor.
Troy: Interesting. Yeah, I just wondered if it's one of these things that it's just something else for us to worry about. And if a lot of us are getting tested and it's a small percentage, or maybe it is, like you said, over 45% . . . I think you mentioned 45% of men have levels under 300. So maybe more of us should be getting tested at some point and we're just not getting tested.
Dr. Smith: Yeah. It's around 40% over the age of 45, you'll see low testosterone levels. And again, it's one of those things where you tend to hit that middle age, people tend to not necessarily be as active, and things like that as well. So there are a lot of things that go into it.
But if we're looking at the actual testosterone itself . . . Let's say you come in, you're low or you're low normal, and you want to try testosterone. There are a lot of things you need to have a discussion with the patients about. Are you interested in having children in the future or any more children if you already have children? What are your goals as far as that goes?
There are multiple different ways to treat testosterone these days or to treat low testosterone, I should say. And kind of having that full disclosure discussion with the patient goes a long way, because there are multiple different modalities of treating it from oral medications to topical medications, to injections, to long-term injectables, to subcutaneous pellets. I mean, there's a myriad of different treatment options that we can discuss.
Scot: And of your patients that you start on therapy, you mentioned that the symptoms can be very broad and caused by a lot of different things. Maybe you're not getting enough sleep. Maybe you've got too much stress in your life. That's why you're low energy. Maybe you're not eating the right foods or exercising. That's why you don't feel good. How many after they get testosterone that come in that have low testosterone actually go, "Yeah, that made a difference," versus, "I'm about the same"?
Dr. Smith: Majority of them. But that also varies via the root that they get testosterone. So I'll talk kind of a little bit about each modality. Oral options is . . . there's a medication called Clomid. A lot of people know it as a fertility medication. Women use it for fertility purposes. But what the medication does is it stimulates your body to produce more testosterone and more sperm. This is a very gradual improvement in testosterone. And a lot of times people don't feel that robust boom, that jolt of energy and things, because it's kind of a low-key slow rise of the testosterone back into the normal range. They don't have that big boost.
And most of the time, when people have that boost, it's from the injection because they're injecting a bolus of testosterone that then is being absorbed into the body and they have their levels shoot outside the normal range. So they feel like Superman. It gives them that rush of testosterone, which you don't get with topicals, the lotions, and you don't get with the oral because it's doing what your body normally did before you didn't create enough testosterone. And so you don't get those super highs that you would have before.
So a lot of patients know, "Oh, man, I do have more energy. I do feel good." The ones who do injections tend to come back and have more of a, "Man, that's great. This stuff is great," because they get that boom, that rush, that spike of testosterone very quickly.
Troy: And then how long until that wears off?
Dr. Smith: So usually people inject on a weekly basis, sometimes every other week, depending on their injection tolerance. And I do have a few patients who inject multiple times per week of low doses because they don't like that roller coaster effect. You do really get a high of testosterone and then it kind of fades out over the course until you do your next injection.
And so that's what they notice. They're like, "Man, I just get this high, and I feel it for about two to three days, and then it kind of wears down and I feel pretty good. And then when I do my next injection, I get that high again." I see that a lot more frequently with people who inject testosterone rather than take oral medications or do topical gels.
Scot: And what about side effects or downsides to testosterone therapy?
Dr. Smith: Man, it's almost like you wrote a script for that or something.
Troy: Talked about the good stuff. Let's talk about the bad stuff.
Dr. Smith: I'm going to make you feel like Superman. And now I'm going to tell you the downside.
Scot: Kryptonite is no good for you.
Dr. Smith: Exactly. You really have to monitor things with testosterone. So testosterone can cause an increase in red blood cell mass, and that in and of itself isn't necessarily a bad thing as long as it doesn't get outside of the normal range too far. That puts you at an increased risk of a cardiovascular event, like a heart attack or stroke.
Now, those incidents are rare, but it's something that we definitely keep an eye on. And that's a reason why we follow these folks with labs regardless of the type of replacement that we do.
Other things that we follow is your estrogen levels can rise because testosterone is a precursor to estrogen. There is a molecule called aromatase that actually converts testosterone to estrogen. Their chemical formula is very, very similar.
Your body likes to keep a ratio of about 10-to-1 testosterone to estrogen, and so the higher your testosterone goes, the higher your estrogen level goes.
And some people will develop breast sensitivity, nipple tenderness, or breast growth from elevated estrogen if their bodies are over-converting to estrogen. And so we watch that closely because that can be bothersome to folks.
And then a couple of the other things, we always monitor PSA in folks that are over the age of 40, or at least I do in my practice because . . . There's not an increased risk of prostate cancer, but if you were to develop prostate cancer, testosterone would feed the prostate cancer.
It's kind of like if you have a match and it's lit, nothing happens. But if you have a match and you pour a gasoline on it, you have a problem on your hands. And so the prostate cancer would represent the match and the testosterone would represent the gasoline. It would help it to kind of progress faster in a way.
And those are the things that we really kind of keep an eye on, especially people with family history or people who have had prostate cancer that we're treating with testosterone, which yes, we do that quite frequently.
Troy: So now that we've talked about the risks of taking the testosterone supplement, let's just say someone is like, "Okay, I've had my testosterone level checked. It's low. I don't want to assume those risks." What's the downside of that?
Dr. Smith: So the downside is you can develop osteoporosis with time. There are some studies that . . . initially some studies came out with testosterone that said testosterone supplementation caused cardiovascular issues, and now it's become the opposite. That's been debunked, and there is some literature out there, I don't know that it's super robust, that said low testosterone can increase your risk of cardiovascular events. So those are the big things of not having enough.
Long term, it's really difficult to assess a lot of those risks, but those are the risks. if you were to just have low testosterone.
Scot: Do you have anybody ever come in that you just are like, "No, it's not a good idea for you"?
Dr. Smith: Yeah. I mean, people who come in with a testosterone level of 600 from their primary care doctor. It's a bad idea.
Scot: Yeah. But I mean low testosterone. Is there ever a time where it's just like, "No, probably not. The risks are too big"?
Dr. Smith: So I think the one thing that I didn't get to with the risks is testosterone replacement will cause sterilization. It will stop you from being able to have children. When you supplement testosterone . . . not all methods of supplementation will hurt fertility, but injections will. Anything that's injectable topical or the long-term injectables or pellets all will cause sterility to a point. And so those things are things that you've got to have those conversations.
So if someone comes into my office and they have low testosterone and they don't want to take the pill like Clomid and they're like, "I just want to do injections, but I still want to have kids in six months," I would say, "Let's hold off until you're done having kids or until your wife gets pregnant, or go donate some sperm so that you can have children if that's your goal, before we start therapy."
Scot: Mitch, given the information that you just got today, are you going to go in? You're going to get some T?
Mitch: I don't know. I'm in a place where I think that after this conversation, I would like to go talk to a men's health specialist, especially if there is a hesitation from primary care physicians to just be like, "Oh, you're in the normal range. You're good." There is a curiosity there. There is an interest there, knowing where I'm sitting at on the levels, if they think it would be something that could help with some of the situations that I'm dealing with right now.
Scot: I guess I'm afraid that it just sounds like another pill. I don't mean that as I don't want to take drugs. I just mean we're all looking for the quick fix, right? So yeah, maybe I'm a little tired. Would I like to lose some fat? Sure. Would I like to have a little bit more muscle mass? Yeah. If I'm in that normal range and on the low end, I don't know. It just feels like I'm expecting too much. I'm going in for the wrong reasons. Does that make sense to anybody?
Dr. Smith: And I don't think you can necessarily . . . I mean, again, I'm not trying to sell testosterone here. I just think that . . .
Scot: No, that's not the point of this. We're just trying to get some information, for sure.
Dr. Smith: Right. But I think that if you want to feel your best and be able to do your thing to the healthiest you can be, I don't think it's a bad thing to come in with the desire to be healthier, to feel better, to have more energy. Again, when you start testosterone therapy, you do have a change in lean muscle mass by about five kilograms switch over from body fat to lean muscle.
Scot: Hold on a second. Hey, Siri, convert five kilograms to pounds.
Dr. Smith: Right. Exactly.
Troy: That's a lot of pounds.
Dr. Smith: It's 2.2 pounds per kilogram.
Scot: It's 11 pounds there. All right.
Dr. Smith: Actually, I said that incorrectly. It's five pounds of fat or two and a half kilograms. My apologies.
Troy: That's still a lot.
Dr. Smith: But still, a five-pound change in your body mass, it can be substantial. It can really help. And again, those are just the numbers that we have from the literature that's out there. And so it can be beneficial.
I don't think there's a wrong reason to come in to look for it. Most patients aren't coming in to be like, "Hey, man, I saw this magazine with this guy Schwarzenegger on it and he was pretty big. I kind of want to get there. Can you help me?" Those aren't the patients that I see.
People come in, they're like, "I'm really fatigued. I feel tired at night. My libido is down. I want to feel better. And I want to see if testosterone may be helpful in that regard." And they're not looking necessarily as a magic bullet or trying to use it as a substance of abuse where they can go and just change their whole body composition. But I think it is very beneficial for a lot of people.
Scot: Troy, where do you stand on it?
Troy: As we talk about this, I just feel like there are so many other things I need to address. That's way down the list. We talk about energy and everything there. I feel like, wow, I'm still trying to figure out how to sleep and those kinds of things. So I'm kind of hung up on that still. We've talked about this and if we talk about it today, I am still kind of curious about it, but I don't think I will be getting tested any time soon. I'll say that.
Scot: I noticed a parallel from another show that we did. You're talking about using testosterone treatments to kind of get over that hump, right? Let's say that you would like to exercise more, but you don't have the energy and you do find you do have a low testosterone. That was almost kind of like using medication for mental health. If you're having challenges with your mental health, it can be really hard to become motivated to exercise or eat well, or maybe you don't even sleep well. So you can take medications for a short period of time until you kind of get those things working. We talk about that Core Four, how they all interact with each other. And then possibly come off of it. Am I understanding that correctly?
Dr. Smith: Yeah. And I think if that's your plan, you've got to look at a way to keep the testicles producing while you do that. If you went to an injectable or a topical testosterone that's going to shut down the body's production . . .
So let me nerd out a little bit with the physiology of this. Your body has these precursor hormones called FSH and LH. And those are the two hormones. They are in both men and women. In women, they regulate the menstrual cycle, and in men, they stimulate the testicles to make testosterone and sperm.
And when you give testosterone, it's a negative feedback loop. And so your body sees there's enough testosterone in the bloodstream and stops sending FSH and LH to stimulate the testicles. And so you've got to do something to keep those testicles producing if you're going to be on testosterone in the short term. That's where other drugs come in.
There's an injectable called HCG that we use to help stimulate. It's an LH analog, meaning it's not LH, but it will stimulate the LH receptor on the testicle. And it will continue to have the testicle continue to produce at a lower level, even though you're giving yourself exogenous testosterone.
And then if you decide to come off after six months or a year or whatever, after you've gotten in shape and you've gotten that motivation, then you don't have this complete drop-off of testosterone where your body has to start making it again where it hasn't for the last year.
Scot: But it would. If you're using a topical solution that's telling your body then not to produce more testosterone, does that mean you're dedicated to that for the rest of your life?
Dr. Smith: You can. Now, you can come off of it. And the thing I tell people is if your body was already not producing enough and you haven't done a darn thing to change that, your body is not likely going to go back to producing more than it was before you started the drug. But then there's always that kind of window where your body has to catch up and it's not producing hardly anything at all and you just feel like garbage.
Troy: But it would come back over time?
Dr. Smith: Yes. And that's the part where the HCG comes in to help it, where you don't have as big of a drop-off. Scot: All right. So now I need to ask the question that I think everybody is wondering. I've heard that if you're on testosterone treatments, your testicles get smaller. Is that true?
Dr. Smith: Absolutely.
Scot: Okay. How small are we talking? Yeah.
Troy: What are we talking here? Yeah. Like raisin-size?
Scot: I mean, for running marathons, Troy, that might not be a terrible deal. Right?
Troy: Thanks, Scot. Much less chafing. Yeah.
Dr. Smith: He's looking out for you, Troy. He's looking out for you.
Troy: Exactly. It'd just be nice smooth surface down there.
Dr. Smith: You'll shave minutes off your time.
Troy: Exactly. All that extra weight.
Dr. Smith: Yeah, you won't have the metronome like you've got now, but it'll work out.
Troy: That's right.
Dr. Smith: But they do shrink, and over time you'll notice that testicular size loss happens the longer you're on testosterone. So people who've been on, say, long-term injectable testosterone, they'll shrink down and be very, very small when you get down to it, almost to raisin-like size that you'll see, which is something that I always talk to people about. And again, that's where HCG can come in if you want to preserve testicular size.
And to some people, that's important. And to other people, I say, "If you're not looking to have kids and it doesn't really matter to you . . ." I've never, ever in my experience of having this had someone come in with their spouse and had them saying, "Man, you know what? I just wish Troy's balls were bigger."
So I don't know how much it really matters, but I think a lot of times it is kind of the vanity side of it, of, "This is what I know, this is what I've had my whole life, and I don't want it to change."
Troy: Well, I will tell you, John, hearing that, I'm reassured that your patients are not talking about the size of my testicles.
Dr. Smith: Nor their wives, for that matter.
Troy: That's good.
Scot: John, let's wrap this up. I think we all know your bottom line. I think I've got your bottom line on testosterone treatments. If you're experiencing these symptoms and you get a test and you're in that low range or below, it could be a very good option to help you get some energy back, to help you with your sexual function, with few downsides, really.
Dr. Smith: Yeah. The downsides are minimal. If you're one of those people who overproduces red blood cells or something like that, we keep an eye on it, but yeah, that is the bottom line. If you feel like it's going to make a difference for you, there's a lot of good that can come from it. And it doesn't necessarily have to be a long-term thing. However, most of my patients that are on it are long term.
And I think if you do have questions, go talk to someone that knows what they're talking about. I'm happy to sit down with people. Most of my new hypogonadism patients/low testosterone folks, I like to spend time going over the benefits, the risks, and everything that is involved is involved so that they have a clear picture of what options they have.
And I do have plenty of people who come in and say, "You know what, doc? I think I am going to try to lose 25 pounds and recheck my testosterone." And then I have others who say, "You know what, doc? I just know myself and I'm not going to do that. And so I'm going to take the testosterone and try to do it that way." I think there's merit both ways. Absolutely.
Scot: John, thank you very much for having this conversation with us about testosterone. Hopefully, this will be helpful to a lot of guys. And bottom line, it sounds like perhaps guys who have talked to primary care physicians, haven't gotten a lot of conversation, it sounds like if you do go to a men's health expert, you've got a little bit more time to discuss through some of these issues and really come up with the right choice for each individual guy.
Dr. Smith: Absolutely. I'd be happy to see anybody in our men's health department at The U. I think we do a great job at taking care of folks and making sure that we go over the options and making sure that we help you make the right decision for you.
Scot: Dr. Smith, thank you for being on the podcast and thank you for caring about men's health.
Dr. Smith: Gents, thanks for having me. It's always a pleasure.
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April 23, 2021
Interviewer: Four ways to naturally boost testosterone. Dr. Jim Hotaling is a urologist and a men's health expert. What can I do?
Dr. Hotaling: Simple things you can do are work on losing weight. Even a 10- to 15-pound weight loss can make a big difference. Also, exercise, particularly anaerobic exercise, such as lifting weights. Eating a balanced diet, trying to avoid processed foods, particularly sugar. That can result in changing energy levels and also mess with the natural circadian rhythms that reflect your testosterone production. And the other big thing is sleep. A lot of men have sleep apnea and that can make a big difference in their natural testosterone production. Testosterone levels are a reflection of your overall health. And if you work on making these changes, you should notice a significant difference in two to three months.
updated: April 23, 2021
originally published: May 30, 2019
What can I do about low testosterone? How to increase testosterone levels without hormone injections. |
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Lifestyle Changes That Can Increase Testosterone LevelsThere are a lot of natural products that claim… +2 More
January 13, 2016
Mens Health
Interviewer: You've been diagnosed with low testosterone. You don't want to do the creams and pills. Are there other things you can do? We'll talk about that next with Dr. Hotaling on The Scope.
Announcer: Medical news and research from University of Utah physicians and specialists you can use for a happier and healthier life. You're listening to The Scope.
Interviewer: Dr. James Hotaling is a urologist and also an expert in men's health here at University of Utah Health Care. And guys that have been diagnosed with low testosterone, what else can you do, other than the creams and the pills?
Dr. Hotaling: There's really only three things that have been proven to naturally raise testosterone levels, the first of which is just weight loss. A lot of men are overweight and don't take great care of themselves. So trying to have a normal weight can help a lot, even losing as little as 15 to 20 pounds can make a huge difference. So that's one thing.
Interviewer: And for guys, that's a challenge because, as we get older, we tend to put on about a pound of fat a year, I hear.
Dr. Hotaling: That's absolutely correct. We have a Men's Health Center that's based South Jordan, and we actually have a nutritionist who a lot of our patients see because it's not that men don't want to take care of themselves. It's just that I think a lot of men view going to the doctor as a sign of weakness. So they need some help to learn how to take care of themselves. So that's the first thing. The second thing is exercise, particularly weight lifting. That's very clearly been shown to boost testosterone and human growth hormone. It's actually the only thing that can boost human growth hormone, which can then also drive testosterone.
Interviewer: Are we talking about Olympic strength-type training, or just going in and building up a sweat?
Dr. Hotaling: Yeah, just building up a sweat. Even lifting weights as infrequently as twice a week for 30 or 40 minutes can make a significant difference and it can also boost your metabolism for one to two days after you do that. So it can help with weight loss. And then the third thing is just trying to eat a healthy diet, avoiding a lot of excess sugar and that kind of thing, which, again, ties into weight loss. So those are really the three . . . and then, I guess, the fourth thing would be getting adequate sleep.
We know that when men are sleep-deprived, that can make a big difference in their testosterone production. We particularly see problems in people who have shift work, where they work at night and their circadian rhythm gets all flipped around. Typically, testosterone peaks at about 4:00 a.m. along with cortisol. So that's all tied to your body's rhythms. And the amount of testosterone you have varies minute-to-minute and hour-to-hour. So those things are all things that can help. I think it's also really important to outline the things that don't help, or haven't been proven to help, if that makes sense.
Interviewer: I bet you alcohol is on that list, isn't it?
Dr. Hotaling: Yeah, it is. Again, that goes . . . that's what the biggest thing is. No supplement has ever been shown to make any difference. There are all kinds of natural testosterone boosters, DHEA. And Utah actually is the national, and perhaps the international, hub of supplements. I mean, there are companies like Essential Oils, which are billion-dollar companies and there is no data that any of that makes any sort of difference. And some of it may even be harmful for men. So that's one thing.
I think the other thing that men should watch out for, we also see a lot of men who take Propecia, or finasteride for hair loss. And that can actually have effects on your testosterone, your sex drive, and even your fertility. So that's another good thing to avoid if you're concerned with that.
Interviewer: So avoid the bad, do the good, and about how long until men start seeing maybe some changes?
Dr. Hotaling: Unfortunately, weight loss, for most people, is a slow process, especially if you're going to have sustained weight loss. I mean, you could lose at most one to two pounds a week. But I think if men stick to a healthy diet and lift weights, they should see a difference in four to six weeks and start feeling better. And there has been data that that's essentially something that's been proven over and over again in the literature. Those are really the key things for men.
And I think the other really important thing men can do is just regularly see a primary care physician. Most men don't. Men seek health care at a rate that's about 30 or 40% lower than women. And part of the reason I'm in here talking to you today is that most of the things that bring men to see a doctor are urologic conditions because they disproportionally impact quality of life, and, we might say, men functions, if you will. So I think it's just really important to get in and see a doctor regularly.
Announcer: TheScopeRadio.com is University of Utah Health Sciences Radio. If you like what you heard, be sure to get our latest content by following us on Facebook. Just click on the Facebook icon at TheScopeRadio.com.
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Why A Doctor Should Monitor Your Testosterone TreatmentsIf you're on testosterone treatments,… +2 More
December 02, 2015
Mens Health
Interviewer: Testosterone therapy, generally speaking it's safe, but there are some side effects. What do you need to know? Why is it important to have a doctor part of your treatments and not just buying it off a TV ad? We'll talk about that next on the scope.
Announcer: Medical news and research from University of Utah physicians and specialists you can use for a happier healthier life. You're listening to The Scope.
Interviewer: If you're on testosterone treatments, it's important to be regularly monitored by a physician to avoid potential risk. Dr. Jim Hotaling is a neurologist and a men's health expert at University of Utah Health Care.
So let's say I'm a man. I saw the TV ad for testosterone treatments and now I'm taking them. Are there some possible risks?
Dr. Hotaling: I mean I think the biggest thing we see very frequently, and I define frequently as I probably see one to two guys a week with this, is that testosterone will make men sterile. It's actually been trialed as a male birth control. It only works on about 90, 95% of men. So it didn't actually make it as male birth control. But that's the biggest thing. It will drop your sperm count to zero in most instances.
The other issue is that it can raise your red blood cell count in some men to unsafe levels. Particularly the injections can do that. It can also cause fluid retention. Theoretically we used to think that it would increase your risk of prostate cancer. But there really isn't a lot of data to actually support that.
And then there's been a lot of data about cardiovascular disease, testosterone and increasing the risk of stroke or heart attack. That really as it turns out, the major study that sort of showed that, which is a paper in a very prominent medical journal, has been shown to be methodologically flawed in a number of different things. And actually there's a lot of data that shows that men with testosterone actually do better from a cardiovascular disease standpoint.
I think generally speaking it's a very safe drug as long as things are monitored appropriately. We check labs on our patients every three to six months for the first year and then annually thereafter. Generally speaking we have very few, if any, adverse events from men being on it. So that in a nutshell are what the major concerns are.
Interviewer: So the people that are probably the target for the television commercials tend to be older. So they might not be concerned about their child rearing days are done. Are there dangers? I always understood that there just wasn't enough research to say whether or not it's safe at this point. And I hear a lot of comparisons to estrogen treatments in women.
Dr. Hotaling: Yeah, so there have been some huge trials done on estrogen treatments. One of the big issues is with that is increasing the risk of blood clots.
Testosterone treatments actually raises estrogen levels in men as well. And that can be an issue. That can get to an unsafe level especially in overweight men. Their fatty tissue has an enzyme in it that will convert testosterone to estradiol which is a female hormone and that can get to unsafe levels.
I think the big issue with testosterone is that we have patients who have been on testosterone for 5, 10, 15 years and we don't have follow up. We don't have the research to know what the exact effects are for being on it for that long. We think generally speaking it's very safe as long as it's used in a reasonable and measured fashion.
Interviewer: So originally in this conversation I was going to take it in the direction of, somebody saw the ad on TV, they're getting the creams in the mail now and I was thinking it's a dangerous thing. But it sounds like you're saying it's not a dangerous thing.
Dr. Hotaling: I think if it's monitored appropriately and men are on it for the right reasons, I think it can make a big difference in their quality of life.
Interviewer: So if I was on it because of a TV ad, it's a good idea at some point to go to a urologist and have some labs done.
Dr. Hotaling: Yeah, definitely. We see a lot of people who are not really appropriately managed. There's a lot of these testosterone clinics that never see the patient and maybe have a phone interview and I think if men are on testosterone they need to see a physician regularly, have appropriate labs monitored, and know that it can make them sterile.
I would say no man of reproductive age who is planning on having children in the future should be on testosterone. There are alternatives that we can use that men have low testosterone and symptoms that are of reproductive age and can boost their testosterone and actually improve, not hurt their fertility.
Announcer: TheScopeRadio.com is University of Utah Health Sciences Radio. If you like what you heard, be sure to get our latest content by following us on Facebook. Just click on the Facebook icon at TheScopeRadio.com.
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Andropause: The Men’s Version of MenopauseWe know women stop producing hormones at a… +2 More
November 18, 2015
Mens Health
Interviewer: Andropause is the male version of menopause. We'll find out more about that next on The Scope.
Announcer: Medical news and research from University of Utah physicians and specialists you can use for a happier and healthier life. You're listening to The Scope.
Interviewer: Dr. Jim Hotaling is a urologist and also a men's health expert here at University of Utah Health Care. Andropause, what is it?
Dr. Hotaling: There is a natural decline in testosterone in men after the age of about 30 or 35, testosterone goes down significantly. One of the things that's really tricky is we don't know what the normal testosterone is in a 20 year old, 30 year old, 40 year old, 50 year old. We know maybe in a 50 year old and above what an abnormal testosterone is, which is usually a total testosterone, depending on who you look at, below 350 or below 300.
But again this is a lab test that varies minute to minute and hour to hour and it has to be checked before about 10 in the morning to be accurate. So if a man goes to get their testosterone checked at 4 pm it's almost always going to be low. One thing that's difficult is the testosterone industry has had the most successful marketing campaign in the history of medicine.
So it literally took testosterone from in 2000 being about a $100 million a year industry, I think this year it will clear 2 or 3 billion. It's actually taught at Harvard Business School, the whole concept of low T as exactly how you should do marketing. And a lot of men come in because they're concerned with that. In summary andropause is real, but and this is the big but, you don't treat a number.
You really only treat patients if they have symptoms of low testosterone and have low testosterone. Ideally on one to two measurements in our opinion and everybody's bias, but urologist are great people to do that because they understand a lot of the issues that impact men's health.
Interviewer: So what exactly is it? Is it just a natural lowering of testosterone? Is that all andropause is?
Dr. Hotaling: Essentially, yes. The testosterone will decline in a man every year past the age of 30 or 35.
Interviewer: And is it the male version of menopause?
Dr. Hotaling: It is in the sense that it's a decrease in hormone levels and everything else. But for women it's a different issue because at some point they stop ovulating. Men really never stop producing sperm. There are people who've produced children in their 90s, which that's a topic for a different day, but men never stop producing sperm.
And it's not as severe as it is in woman. It's a very gradual decline and at some point, in some men, it declines to a point where it does cause symptoms and that is where I think there is some resemblance to menopause.
Interviewer: And that's where you as a urologist or a men's health expert would perhaps then consider doing some sort of therapy?
Dr. Hotaling: Yeah, that's correct and typically the therapy is testosterone replacement. There are other medications we can use. The downside to testosterone replacement is it will make men sterile, some men permanently. Most men not. But we can use other medications to actually boost testosterone and keep men's' fertility intact.
There are also some surgical procedures, one in particular we can do to actually help increase a man's testosterone.
Interviewer: So decreasing testosterone or going through andropause is just normal?
Dr. Hotaling: Yeah, it is normal and I think that's the key thing to understand. The testosterone companies would have you believe that you should treat a number. And what's tricky about testosterone is anyone, no matter what their testosterone starts at, will feel better when you put them on testosterone. That doesn't mean that everybody should be on testosterone and I think that's the real challenge.
Announcer: TheScopeRadio.com is University of Utah Health Sciences Radio. If you like what you heard, be sure to get our latest content by following us on Facebook, just click on the Facebook icon at TheScopeRadio.com.
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The Facts About Low Testosterone TreatmentYour energy level is down, you’re putting… +3 More
November 18, 2013
Mens Health
Announcer: Medical news and research from University of Utah physicians and specialists you can use for a happier and healthier life. You're listening to The Scope.
Interviewer: If you watch any TV at all you can't escape the ads, ads for you need testosterone therapy. It looks like it's pretty easy to get, but should you get it? That's the question. Right now I've got with Dr. Tom Miller, University of Utah health care.
Dr. Tom, for a guy that's over 30 years old, it's been scientifically proven that testosterone levels start dropping at that point. Should I be ordering some of this testosterone online? I mean after all, I want to look like that guy.
Dr. Tom: I think the question, Scot, is why do you think you need it? What's different?
Scot: So, the ads tell me my energy levels have dropped, which they have, that I start putting on more body weight, that my mood is affected, and my sex drive is decreased. Testosterone is going to cure it. It's kind of cure-all is what they're telling me.
Dr. Tom: That's a great concern. That's a concern of many men, and women, throughout the country, but the real question is are there different causes for those things you mentioned? There are many causes for people being a little overweight, feeling a little fatigued. It isn't just testosterone; it's a whole basket full of causes.
Scot: So, if I came into your office, and I gave you those symptoms, and I said that I want testosterone what would you say to me? Where would you start looking?
Dr. Tom: I would ask a few questions. One I'd ask, "What's your sex drive like? Has it dropped off? Are you interested in sex? Do you have the same drive that you had five years ago?" And if the answer to that is no and that you were concerned about it, I'd then go ahead and measure your testosterone level.
Scot: Okay.
Dr. Tom: But I'd also ask you a number of other questions. If the testosterone levels came back low, then we might do a trial of testosterone replacement, and we would then monitor how you felt. Did it make you feel better over the course of time that we try the medicine? If not, it might be wise to stop it.
Scot: So, let's back up for a second, these ads that I'm seeing on TV, I can just order without a doctor's prescription?
Dr. Tom: No, you have to have a doctor's prescription. There's a doctor on the other end that's asking a set of questions.
Scot: So, when I make that call, there is a doctor?
Dr. Tom: There's somebody that has to write the prescription.
Scot: Got you. How do they know how much I need, because it sounds like you would do tests to find out what the actual level is? It sounds like they're just asking me some questions and if I pass they're going to write me the prescription.
Dr. Tom: That's probably true. I can't attest what other things that they do, I'm not sure that's the best way to get health care. Basically you're telling them that you need testosterone, and they're saying, "Fine. Answer these questions. Here's your prescription." I'm not sure that's the best way to try to define what your problem is. As I mentioned before, the causes of fatigue and weight gain there are multiple issues related to that not just testosterone.
Scot: So, let's pretend that I come into you because I want to be a little smarter about it. You ask me some questions; you decide to run some tests. You find I'm in the normal range, on the low end of the normal range. Would you do anything at that point?
Dr. Tom: I probably would counsel you about your lack of sexual drive. Well, I'd seek more information about that, and it might me that there are other reasons for that aside from the fact that the testosterone is in the borderline range. I suppose if you really wanted to try it we could do a trial.
Scot: Sure.
Dr. Tom: I'm not opposed to that if the patient thinks that's right, but I try to give them a realistic expectation. Also tell them that, "Look, it's not a wise thing to take medicine if we do this for several months and you find there's no difference, and you're honest with yourself about it." Just as with any medicine, in my mind, it doesn't make sense to take it if you really aren't getting a benefit from it.
Scot: So, let's take a look at these ads; they promise me so many things. Let's talk about the benefits of testosterone therapy, just from a strict benefit. Why would I, as a man, even come to you and talk to you about it?
Dr. Tom: Certainly, if you had low levels, it might be affecting your sexual drive, you might have some fatigue, you might have less muscle mass then you were used to. In that instance, if you were replacing testosterone, it might help you quite a bit; you might have a great improvement. The problem though, long term, is we don't really know if the side effect . . . we don't know what the side effects are of testosterone replacement over the long haul greater than five years. We just don't know that yet.
Scot: So, this is kind of the risks part right now, is we don't know what the risk are.
Dr. Tom: We don't really know what long-term risks of testosterone use might be, replacement. There are a number of men that I know who have low testosterone and they don't notice any difference. So, do you replace testosterone by testing for it in men who are low? The answer is I don't think we really know. We don't have enough information. We do know that testosterone helps maintain bone integrity and strength but we're not at the point where we say screening for testosterone is a thing to do.
Scot: So, it falls off as I turn 30, and as I get older. When you're testing, are you testing for the normal range for, say, a 55-year-old man, if I'm 55, or were you...?
Dr. Tom: I want to back you up a little bit; testosterone may decrease variably in men so it's not the same as menopause in women.
Scot: Okay.
Dr. Tom: So, when women enter menopause their levels of estrogen drop precipitously. The same is not uniformly true in men. Some men have lower levels of testosterone over time, but not all. So, it's unclear which men would have low testosterone and others have normal testosterone; we just don't know yet. There's not a recommendation to screen all men for testosterone levels.
Scot: So, you really can't say how much should a 50 year old man have?
Dr. Tom: Well that's correct, I mean because we don't screen.
Scot: Got you.
Dr. Tom: We don't test for testosterone as part of an annual exam in the same way that we test blood pressure or test cholesterol or test blood sugar.
Scot: So, your advice is don't order the stuff on TV because you're playing with something that...?
Dr. Tom: My advice is that if you have questions about the way you feel, whether you have fatigue or decrease in energy level or a decrease in your sexual drive, then you should probably talk to your physician about that and decide if testing your testosterone level is right for you. Nothing wrong with that.
Announcer: We're your daily dose of science, conversation and medicine. This is The Scope, the University of Utah Health Science's Radio. |