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The Intermountain West has some of the rates highest of suicide and depression in the U.S. Studies suggest that the statistics may result from changes in brain chemistry that occur when living at high altitude. Psychiatrist Dr. Perry Renshaw investigated whether dietary supplements can alleviate high altitude depression that is resistant to treatment by standard SSRI antidepressants. He discusses what he has found so far, and the surprising remedy his group is pursuing. His work is open for crowdfunding at Experiment.com.