How Vaccines During Pregnancy Protect Moms and Babies Before and After Birth |
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Ep. 4: Sun Protection & Skin CareSummer's here but sun protection is… +7 More
From Hillary-Anne Crosby
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Luke Johnson, MD (University of Utah Health Dept. of Dermatology), Michelle Tarbox, MD (Texas Tech University Health Sciences Center)
June 24, 2021
Health Sciences
https://healthcare.utah.edu/dermatology/skincast/apple-podcasts-skincast-logo.png Dr. Tarbox: Hello, this is Skincast, the podcast about skincare. My name is Michelle Tarbox, and I'm a dermatologist in beautiful sunny Lubbock, Texas. Dermatologists are medical doctors who specialize in the care of the skin, hair, and nails. And joining me is . . . Dr. Johnson: This is Luke Johnson, dermatologist in Salt Lake City, Utah, with the University of Utah. Dr. Tarbox: So we're here to talk to you about how to take the very best care of your skin. On this podcast, we will mention specific products, but we are not sponsored by any of these products. We have just found them to be useful in our clinical practice. We have no conflicts of interest with these. We just want to give you the tools to take the very best care of your skin. Dr. Johnson: And today, we're going to be talking about how to protect your skin from the dermatologist's age-old enemy, the sun. Dr. Tarbox: Especially living here in beautiful sunny Lubbock, Texas, I swear that the sun in our area could really be a comic book villain. It is quite strong. So we want to talk about how you protect yourself from the giant ball of heat in the sky. So there are a lot of reasons why we should protect our skin from the sun. One of them, of course, is to reduce the risk of skin cancer. This is a very important part of our overall healthcare and it's something that we need to do all throughout our lives. There are some statistics that are sometimes thrown around that I think sometimes discourage people, one of them being that you get something like 90% of your lifetime sun exposure by the time you're 18 years old. That is actually not true. You get about 20% of your lifetime sun exposure by the time you're 18 years old. So if you are an adult and you're just starting to look at taking good care of your skin, you're not too late to the party. But you do want to start taking care of your skin early, and if you do have children, you wanna start them with good, safe sun habits early as well. Dr. Johnson: I like to think that there are three main reasons you want to protect yourself from the sun. One is your skin cancer risk. Two is something called photoaging. Sunlight makes you look older. And three is, of course, sunburn, though I feel like that's a little bit tangential. Though, that's often what a lot of us think. In terms of the skin cancer risk, dermatologists I think are pretty good about getting the word out about melanoma, which is the most dangerous kind of skin cancer. But there are other kinds of skin cancer as well, and the sunlight increases the risk of all of them. Dr. Tarbox: Absolutely. And it does that by causing mutations in our DNA. So, unfortunately, the mutations that we get in our DNA from sun exposure, from solar radiation, don't give us superpowers like the X-men or something like that. Instead, it causes us to develop skin cancer, and it causes our skin to prematurely age. Dr. Johnson: Yes. So your DNA sits in the cells in your skin and the ultraviolet radiation from the sun can make changes in that DNA that makes them more prone to turn the cell into a cancerous one. Dr. Tarbox: The other thing the sun can do is it can damage the collagen in your skin. And the collagen in your skin is what gives youthful skin that kind of bounce and turgor that make it look plump and healthy and prevents the wrinkles from forming. Collagen is our best friend when it comes to anti-aging, and the sun is its mortal enemy. Dr. Johnson: That's why people who have seen a lot of sunlight in their lives and are now older look very wrinkly. So you can minimize that by protecting yourself from the sun as much as you can. Also, there are certain types of ultraviolet radiation that penetrate window glass as well. So even if you're planning on spending all day on a road trip driving in the car, still put on sunscreen because that UVA radiation comes right through the windshield and still causes that aging process. Dr. Tarbox: Exactly. There are like three flavors of UV radiation that we sometimes talk about. In the news recently, you may have heard about UVC radiation. We don't actually experience that here on earth because the ozone layer filters that out, but it can be used in laboratory settings to sterilize things. And in the news, people have been talking about using certain kinds of air filters that have UVC radiation to help sterilize that. Now, you wouldn't want to have these indoors on people because it can cause problems with your eyes. So you don't want to be exposing your eyes to UVC radiation. Fortunately, like I said, that gets filtered out by the ozone, so we don't have to deal with that one. UVB rays do make it to the earth. We traditionally think of these as the burning rays. These are the ones that are going to have their greatest intensity at midday in full sun. And these are the ones most of us think of when we think about protecting our skin from the sun. We think about the UVB rays that cause burning. But what about those UVA rays, Luke? Dr. Johnson: Well, they're the ones that penetrate window glass. They also tend to be the ones that are involved in tanning beds. So it's not like a tanning bed doesn't increase your risk of anything. It definitely can increase that aging process. Dr. Tarbox: And that UVA, I like to say it stands for aging. Because UVA actually is the flavor of UV radiation that gets the deepest into the skin. It penetrates the deepest into the skin and gets to that collagen that it can then degenerate. So that's what causes those aging changes, those UVA rays. Speaking of tanning beds, some people think they go to the tanning bed to get vitamin D synthesis. However, because UVB rays burn you . . . most tanning salons don't like to burn their clients because their clients don't come back. And so the UVB rays are usually not in tanning beds, but the UVB rays are the ones that are necessary to make vitamin D from the sun. Now, I'm a dermatologist. I'm a religiously sun-protected human being since the time I was about 15 years old and figured out the connection between skin cancer, sun, and aging. And I have perfect vitamin D levels because I take an oral supplement. I choose not to use my face and my skin to make my vitamin D at the cost of it increasing skin aging and skin cancer. Dr. Johnson: So, if you're going to be out in mid-July at the beach at 2:00 p.m. with no clothes on except your swimsuit, I think most people feel like that's a good time to protect yourself from the sun. And that's true. But it's important to remember that there's always ultraviolet radiation out there because the sun is shining on the earth. So even on overcast cloudy days, even if it's 4:00 p.m., even if it's winter or fall, there's always ultraviolet radiation out there, which can cause these changes associated with skin cancer and increase your risk of photoaging as well. So I put on sunscreen every day regardless of what I'm planning to do that day. Dr. Tarbox: Me too. It should be part of your routine like brushing your teeth in the morning. And I actually tell patients when they're trying to get in that habit to actually keep it near something they do every day. So, if you have space, keep an extra toothbrush. You're brushing your teeth, you're looking at your sunscreen going, "After I'm finished brushing my teeth, I'll put on my sunscreen." Dr. Johnson: Speaking of sunscreen, it's one component of a multi-component approach to protecting yourself from the sun. So, in brief, sunscreen is good. Also, stay in the shade, wear hats, wear sun-protective clothing, and wear sunglasses. And we can talk a little bit about each of those in a bit more detail. Dr. Tarbox: I like that. I like to think of skin being protected from the sun as sort of like a team sport. So your quarterback is your sunscreen, of course. It does a lot of the hard work for you. But you have to realize that there are some limitations to sunscreen. First of all, there are places it's hard to apply, like on your scalp. And there's also a difficulty with keeping it at its highest functioning level throughout the day because you have to reapply sunscreen about every two hours. So you can add to your sun protection regimen by utilizing sun-protective clothing and, of course, sunglasses to protect your eyes. Dr. Johnson: And the skin around your eyes. I've heard some people complain that they don't like putting sunscreen on their face because it stings their eyes. Well, just don't put it all that close to your eyes, but put on sunglasses. A lot of my patients have questions about what specific sunscreens I recommend. So here's some of the deal with sunscreens. We usually recommend that you use SPF 30 or greater. Higher SPF is better, but it's not like 60 is twice as good as 30. It's just a bit better, but higher is better. You also want to make sure you use enough of it. So our first challenge as dermatologists is to get people to actually use sunscreen, and our next challenge is to get them to use enough. Dr. Tarbox: That's absolutely right. So you have to use about a shot glass full of sunscreen to apply to the areas that are usually exposed to the sun. One thing you don't necessarily want to mix though is sunlight and a lot of alcohol, because there have been some studies that showed that that potentially can increase the harmful effects of the UV radiation. So we like to say here on Skincast, “Don't Titos and tan.” Dr. Johnson: So that shot glass should be full of sunscreen and not something else if you're planning to be out in the sun. And you mentioned to reapply every couple hours, and that's true. So another challenge we have as dermatologists is to get people to keep using the sunscreen. So it just sort of wears off in a couple of hours because the chemical components in it get used up because they're doing their thing protecting you from the sun, or the physical blockers get washed or sweated or wiped away. Dr. Tarbox: Absolutely. And one pro tip that I like for people who are active outdoors, who have trouble with the sunscreen kind of getting in their eyes when they sweat, is you can actually get the little wax sticks that are kind of like a Chapstick that have sunscreen on them, which are also a nice thing to use if you have to put sunscreen on a child's face because they can't get it in their eyes on accident. And if you put a little bit of that wax-based sunscreen over each eyebrow and leave the space between the eyebrows uncovered with that kind of sunscreen and use the other one everywhere else, it'll keep the sweat from dripping down into your eyes and carrying the sunscreen with it. Dr. Johnson: I think it's a good point to mention that there are different products available. A lot of people think about sunscreens just as sort of the standard lotion-y, creamy stuff that they slather on themselves. But these days, the sunscreen manufacturers have developed a lot of different ways to put this stuff on your skin. And a lot of people might feel that it's more convenient or it feels better for them. Dr. Tarbox: Yeah, I think the most important thing is to find a sunscreen that you like using, because if you get the very best whatever highest SPF sunscreen but you hate applying it, and you don't like the way it smells, and you don't like the way that it feels, you're not going to use it. So you need to get one that you like to use and that you're comfortable using. Dr. Johnson: And they all seem to be fine. So there are spray sunscreens, which I find quite convenient. They're a little bit tricky because you've got to keep your eyes closed if you're putting them on your face. Or you spray them on your fingers and hands first, and then put them on your face. You've got to watch out putting them on children because children will sometimes breath in at the wrong time or keep their eyes open. They're also technically flammable. So sometimes people are having campfires, and that's when they're putting on sunscreen, so watch out for that. But otherwise, sprays are a fine way to apply sunscreen to your body if you find them convenient. Dr. Tarbox: Yeah, that's definitely a good thing to bring forward there. So just like you wouldn't go near an open flame and spray a can of hairspray, you wouldn't want to use any kind of spray sunscreen that has an accelerant in it. So once that does dry, you are no longer highly flammable. Just make sure the sunscreen is dry before you go near any heat sources. Dr. Johnson: There are also sunscreen sticks. I think you mentioned these. They look a bit like deodorant sticks, but you can just sort of rub them on your arms and they're pretty convenient. I know Neutrogena makes a good one. I think it's called Sport Stick or something like that. And then there are also powders. So I've had some big, strong, tough, manly men who just don't feel like they want to put lotion on their skin. So I say, "Well, some of my patients like these powders, because you can just sort of brush them on your face easily and then throw them on the back of your pickup truck and be off to your manly man duties." Dr. Tarbox: I like that. That should be a brand. There should be manly men sunscreen. What do you think? Dr. Johnson: I think we should make it. Dr. Tarbox: It should be non-fragranced and it should not have any kind of color to the skin. I like the idea of a powder. Dr. Johnson: And it should have a picture of me flexing on front. Dr. Tarbox: I think that would be perfect. Dr. Johnson: So, last year, there was also a medical study that showed that the chemical components of sunscreen get absorbed into your blood. It didn't show that anything bad happens when they get absorbed into your blood. And my personal feeling is that probably nothing too horrible happens because we've been using them for decades and nothing too horrible has happened to the general public. But it does show that they get absorbed into your blood and we probably need more medical studies that look into what that means. So, because of that concern, I usually recommend just the mineral-based sunscreens. Those are sunscreens containing zinc or titanium as the only active ingredients. I recommend those for children specifically. For adults, I don't think it matters quite so much. If you are worried about sunscreen chemicals being absorbed into your blood, then stick with zinc or titanium sunscreens because we know those stay on the skin. Dr. Tarbox: They have some really good sunscreens that are actually zinc only that are very gentle. Neutrogena makes a good one. Some of them are also produced with a process called micronization, which makes the particles of the physical sunscreens, which are both metals, zinc and titanium, very much smaller so that they don't leave a sort of gray cast on skin, especially skin that's got a darker color. Dr. Johnson: I like the Neutrogena . . . I think it's called Clear Touch or something like that. It's just zinc or titanium. It rubs on easily. I find it some of the mineral-based sunscreens kind of muck up clothing a bit, but this one seems to be good. Dr. Tarbox: And some people are sensitive to sunscreen ingredients. The ones that I think are the best for people who have sensitive skin are a product line called Vanicream, which you can get most Walgreens drugstores. Vanicream is made to be very hypoallergenic. They have a really good sunscreen, their Vanicream Sports sunscreen, which is SPF 35. I also really like CeraVe's sunscreen. It's a nice sunscreen for people who have sensitive skin as well. And it's made to be sort of like a nice little extra skincare product. So there's actually some niacinamide in there, which is a B vitamin that's an anti-inflammatory and it's a skin healthy ingredient. Additionally, they also have some hyaluronic acid in that sunscreen. Dr. Johnson: CeraVe is a good brand. I like it for my daily facial moisturizer that has sunscreen in it. So CeraVe AM is what I put on every day. It has some SPF 30 and protects my skin from those photo-aging effects of that radiation. Dr. Tarbox: I like that. And earlier we were talking about the fact that some of the mineral sunscreens can leave a little bit of a cast on skin of color. I think it's also important to mention that everybody needs to protect their skin from the sun. So there is not a person of any skin color that's 100% without risk for developing skin cancer. And sometimes people have gotten that information either through the media or unfortunately sometimes even through medical practitioners. So it is important to protect your skin from the sun no matter what color your skin is as a baseline. You wanna make sure that you're keeping yourself healthy and taking good care of yourself. If you are a person of color, you do need to work harder to supplement the vitamin D, however, because that or that turns to be a little bit of a greater percentage of vitamin D deficiency in patients of color. So very important to protect your skin from the sun. We talked about also seeking the shade, which is important. The middle of the day is really when the sun's rays are at its most intense. So that's usually between about 10:00 a.m. to 2:00 p.m., with the noon hour being sort of the witching hour when you get the most UV radiation on the earth's surface. So trying to stay out of the sun if you can during those times is a good idea. But what if you can't stay out of the sun right then? Dr. Johnson: Well, I like hats. We like hats with wide brims. I have a nice wide-brimmed hat that makes me look super cool when I'm walking around outside with my kids and my kids are all wearing big wide-brimmed hats and everyone thinks, "That must be a dermatologist walking by." Dr. Tarbox: Yeah, I feel like you can always pick out the dermatologist's kids at the beach. So you can do that. You can do that sun-protective clothing. Sun-protective clothing has something called a UPF, and it's UV Protective Factor. And that will actually be on the label typically. Most sun-protective brands have a UPF of 50 and it's analogous to an SPF. The companies that we like that do that include Coolibar, which is a sun protection clothing manufacturer. They have awesome clothes, and they go on sale frequently. There's also one called Sunday Afternoons, which is very cute. And then there's UV Skinz, and Skinz is spelled with a Z, which I thought was fun. Dr. Johnson: There are also some generic brands, if you will. So, if you just look on Amazon or Google for sun-protective clothing, you can find some. And they're light and breezy and they're meant to be worn when it's 90 degrees outside. So it might sound miserable to wear long-sleeve shirts when you're out in the summer, but that's what these are intended for and they're pretty good. I have a number of them myself, and I don't feel miserable wearing them outside, Dr. Tarbox: I actually find them less hot when I'm wearing them. There are some products that are made that are in sun-protective line that are actually made from bamboo fiber. And bamboo fiber is naturally a couple of degrees cooler than the ambient temperature. So it's a very comfortable thing to wear. So, Luke, what are some sun myths that sort of circulate? Dr. Johnson: We mentioned a few of the myths, like that SPF 60 is twice as good as SPF 30, or that if you're old, it's too late to protect yourself from the sun. Not so. There's also this myth about having a base tan. So I've had some people tell me that they're going to go to the tanning salon to get a base tan before their trip to Hawaii or something. Don't be fooled. That doesn't help. Dr. Tarbox: Yeah, the base tan might make you feel more comfortable in your swimsuit, but spray tans are a good alternative. Spray tans are actually just made out of a three-carbon sugar that gets sprayed on or applied on the outside levels of the skin. This chemical does not absorb it all into the bloodstream. And it basically goes through the same reaction that bread goes through in the oven that causes it to brown. It's called the Maillard reaction, and that's what gives that color. The newer products have actually been very elegantly composed to remove sort of the traditional fake tan smell, which is very nice. And a lot of products can also be used kind of gently and daily to build up gradual color in a nice even way. Dr. Johnson: Well, listeners, I hope that that gives you some ideas about why it's important to protect your skin from the sun and some good ways to do it. Dr. Tarbox: We are very happy to be able to educate you about how to protect yourself and we're very grateful for this opportunity to visit with you. We want to thank our institutions for giving us support to do this podcast and encouragement to help people take better care of their skin. Dr. Johnson: Yes, Texas Tech Dermatology and the University of Utah Department of Dermatology. And if you consider yourself a real dermatology nerd, Michelle and I have another podcast called "Dermasphere," where we cover some of the latest research in dermatology. We'll see you guys next time.
Good skin protection is important for skin health at every age and in every season.
Dermatology |
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Stick with the Basics to Protect Yourself and Others from CoronavirusStaying physically distant from other people.… +7 More
April 21, 2020 Interviewer: Protecting yourself and others against COVID-19. It seems like the further and further we get into the pandemic, the more ideas and more things people are doing to protect themselves. But Dr. Richard Orlandi from University of Utah Health says, actually, some of the best things you can do to protect yourself and others just come right back to basics. Can you give us an idea of what the hierarchy of things are that we really should focus on that we know protect ourselves and other people? Dr. Orlandi: Staying physically distant from one another. People have called this social distancing, and I prefer the term physical distancing, because we still want to interact with one another. But the idea of staying six feet apart so that if I cough or sneeze, that's not going to hit you, or if you cough and sneeze, it's not going to affect me. We know that that's how this virus is spread is either through respiratory droplets being sprayed out or if I touch my eye, my nose, my mouth, get those respiratory droplets on my hand, I touch your computer and then you type and then you touch your eye. And so that's how those things are happening. So that physical distancing is really important. When we're not able to be physically distant, masking is important. Now, a couple of weeks, you and I talked about how masks were not as important because we were thinking of them in terms of I'm going to put a mask on so you don't get me infected. But we're changing the way we're looking at that, and really I'm going to put a mask on so I don't infect you, even if I don't have any symptoms, because we now are understanding that people may be able to transmit this virus the day before or a couple of days before they really have that fever, muscle aches, shortness of breath, coughing type of flu-like symptoms. That's going to help so that when I go to the store, I'm not spreading it to everybody else. Now, if all of us do that, we're keeping one another safe, and that's a great way that we can show our citizenship, our care for one another. Interviewer: So it comes down to droplets, keeping your droplets away from other people, keeping other people's droplets away from you. And you do that by physically distancing yourself and also remembering not to touch your hands to your eyes, your nose, or your mouth. But Dr. Orlandi says this time of year, in particular, that can be really challenging. Dr. Orlandi: Doggone it. In allergy season, what happens? Your nose itches. Your eyes itch. Try to avoid doing that. Or if you do it, if you rub your eye and you rub your nose, just hand sanitize afterwards. Hand washing is so important. Sanitizing the surfaces around you. If you work in an office where a lot of people are still coming to work, get those wipes out and wipe down your work area. Wipe down the doorknobs and things like that where we're all commonly touching. Interviewer: And if we all keep it up and do it really, really well, it will make a difference. Dr. Orlandi: Literally, what people are doing here in Utah, it's saving lives. And I would say stay physically distant but socially close. Check on your neighbors, check on your family and stay connected, but do it in different ways. Do it through video platforms. Do it through the phone. Go for a walk. Stay six feet away from one another. If there are things that we can do to slow down the spread of that virus, that's probably the best thing we can do for our healthcare systems and for our society and to get our economy back up and running as fast as we can.
The basics are still the best methods when it comes to protecting yourself against coronavirus. |
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Seven Questions for a DermatologistOn this episode of Seven Questions for a… +6 More
May 31, 2017
Health and Beauty Announcer: Seven questions, seven answers. It's "7 Questions for a Specialist" on The Scope. Interviewer: We're here with Dr. David Smart, dermatologist at the University of Utah and these are seven questions to ask a dermatologist. Dr. Smart, what is the most common skin issue in Utah? Dr. Smart: Brown spots. That's what I'm going to go with. Brown spots is the most common issue in Utah. Interviewer: What is the absolute best thing I can do for my skin? Dr. Smart: Don't smoke and protect from the sun. I'm going to go with two. That's cheating but that's all right. Interviewer: What is the absolute worst thing I can do for my skin? Dr. Smart: Smoking. Interviewer: What is the one thing you know about skin that everyone should know? Dr. Smart: Protecting your skin from sun damage will keep you looking better, younger for longer. Interviewer: Is there any foods that are particularly good for my skin? Dr. Smart: Yes. Foods that are high in antioxidants, mostly fruits and vegetables do a lot to protect your skin and rejuvenate it. Interviewer: What is the best technique to keep my skin moisturized? Dr. Smart: Frequent application. Interviewer: Why do you chose to specialize in dermatology? Dr. Smart: The doctor patient relationship. Patients have very visible concerns that they're very worried about that. So they're happy to come to the doctor. It's very gratifying. The interaction is very positive. Announcer: If you like what you heard, be sure to get our latest content. Sign up for a weekly content updates at thescoperadio.com. This is The Scope, powered by University of Utah Health Sciences. |
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Does a Suntan Protect Against UV Rays?Does getting a rich golden-brown tan offer… +6 More
August 01, 2014
Cancer
Health and Beauty Interviewer: Suntans. Do they offer protection from skin cancer? We're going to examine that next on The Scope. Announcer: Medical news and research from University Utah physicians and specialists you can use for a happier and healthier life. You're listening to The Scope. Interviewer: We're with Dr. Doug Grossman. He's an expert in early diagnosis and treatment of skin cancer at Huntsman Cancer Institute. So I need this answer from a professional, from the guy that knows. I've always been under the impression if my skin starts tanning it's the natural response to the sunlight to let less sun in so that actually is giving me more protection. Is that accurate or not? Dr. Doug Grossman: Well it's true that the suntan is a natural response of the skin trying to protect itself from the damaging UV rays and so actually the UV exposure generates a signal response in cells in the skin that causes more pigment to be made and this ultimately does protect the skin and so if you do have a suntan then you're going to be more resistant to future sun burning. The problem is that you're also damaging the skin in this process and in fact the sunburn or suntan response is actually an indicator of damage to the DNA. What happens is the UV rays interact with the DNA and initiate this response that signals the cells to make more pigment but it's actually a reflection of that damage that you're incurring. And so even after a few weeks if the sunburn, the tan has resolved, that damage has still been done. And it can accumulate and persist for many years. Interviewer: So gradually building up my suntan to prevent skin cancer, it could prevent a sunburn. Dr. Doug Grossman: Right. Interviewer: But the damage is still happening to the skin that could cause skin cancer. I'm getting no protection from it from what I understand. Is that correct? Dr. Doug Grossman: Right. That's correct. Interviewer: So what does that mean? Dr. Doug Grossman: The tan is going to protect you against some future UV exposure but it would be better to not incur that exposure and damage in the first place. Interviewer: And also, like wear long sleeves or wear some sort of a sunblock or something of that nature would be much better, right? Dr. Doug Grossman: Right. Well, I tell patients if they want to have a tan and look tan the safe way to do that is to apply topical products or a spray tan and they can look quite realistic and that's totally safe. Artificial tanning in that way doesn't provide any protection against future exposure but that's the safe way to look tan. We really discourage patients from using tanning booths. We know that tanning booths increases skin cancer risk, it at least doubles melanoma risk and so we definitely discourage that. Interviewer: I seem to remember at a tanning place one time the guy was telling me, "Oh no, this is okay because the damaging rays aren't in the suntan booth." Dr. Doug Grossman: Well, generally in the tanning booths they use longer UV wavelengths that are lower energy so it doesn't cause sunburn but does initiate the tanning response and you get delayed tanning. Interviewer: Which goes right back to what you said earlier is that that's an indication that you're getting cell damage. Dr. Doug Grossman: Correct. Interviewer: And that cell damage, so we all love our tan so much let's get into this cell damage a little bit more because I feel as though maybe if people heard what's really going on and how damaging it can be they might, you know, make a different choice. I've heard it described as bullets to the DNA. Dr. Doug Grossman: There are different ways that UV can damage the skin. The UV can directly interact with the DNA and damage it in that way. This could result in mutations and so that when the cells divide- Interviewer: Which all cells do. That's what cells do. Dr. Doug Grossman: That's right. That's right. Particularly in the skin because the skin is always turning over and so you can introduce mutations that way. UV radiation also generates what we refer to as oxidative damage. These are chemical species that are generated in the skin upon UV exposure that damage all parts of the tissues: the proteins, the cell membranes. So there's that type of damage as well. Interviewer: Somebody might think, "Well, I've damaged my skin. It dies. It sloughs off." But what happens is when that cell divides now you've got these mutations that could lead to skin cancer. Am I making... Dr. Doug Grossman: Right. And so again the skin does turn over. Many of the cells that are dividing will ultimately die and be shut off. Changes in those cells are not going to result in skin cancer. However, there are what we call skin stem cells that are very long-lived that give rise to the cells that ultimately continue to grow in the skin and you generally don't lose those cells. And so if those cells accumulate this damage and these mutations they can ultimately give rise to skin cancer. Interviewer: And how bad is skin cancer? Dr. Doug Grossman: It's a range. It's a spectrum. Many skin cancers if they're detected very early are quite easy to treat and they are very localized in the skin and we can remove those with a small surgical procedure. Interviewer: And I'd imagine once you start getting that it's going to continue because those cells are damaged. Dr. Doug Grossman: If you get skin cancer in one location then your risk for getting it in another location increases because you have all these both genetic environmental risk factors that have led to the first skin cancer. We know that patients that have a skin cancer generally about half of them will get another one within the next couple of years. Interviewer: Yeah. Dr. Doug Grossman: That's primarily non-melanoma skin cancer. The melanoma skin cancer which is much more serious... Interviewer: More on the other end of the spectrum. Dr. Doug Grossman: Because it can spread can be a lot more unpredictable. That can occur in young patients, it can occur without much warning. About a third of melanomas are not related to sun exposure. And so we advocate all patients to monitor their skin on a monthly basis. Anything new or changing should be looked at. But we do know that over two-thirds of melanomas are related to sun exposure. Interviewer: Any final thoughts on this topic? Dr. Doug Grossman: I think my main message would be, be aware of your skin. It always surprises me how often we pick up melanomas in patients that had no idea that something was on their back or somewhere else on their skin that just because they weren't monitoring. I recommend again once a month that patients look at their skin, have someone else look at your scalp, look at your back, the areas that you can't monitor well on your own. Anything new or changing or that looks different from other spots on your skin would be something to get checked out. Announcer: We're your daily dose of science. Conversation. Medicine. This is The Scope. University of Utah Health Sciences Radio. |