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For the first time, the Anticoagulation Forum has published clinical guidance statements for managing blood clots in the veins, or venous thromboembolism. Dan Witt, PharmD, Professor of Pharmacotherapy at the University of Utah, is a lead author on statements regarding warfarin management. He explains what prompted the new set of guidance statements, how they differ from existing guidelines, and why they will be of value to practitioners who encounter this condition.